Semaglutide: The Truth About the Magic Weight Loss Drug Hollywood Celebs Are Injecting

Semaglutide aka Ozempic is a GLP-1 agonist that's been around for a long time, suddenly Hollywood elites are now promoting it for fat loss. Here's the science you need to know. Sponsored: Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE Save 15% with code podcast at checkout Video and Images: https://bit.ly/3wpnpAE Research Mentioned: Wilding, J. P. H. et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New Engl J Med 384, 989–1002 (2021). Sharma, D., Verma, S., Vaidya, S., Kalia, K. & Tiwari, V. Recent updates on GLP-1 agonists: Current advancements & challenges. Biomed Pharmacother 108, 952–962 (2018). Show Notes: 0:20 Semiglutide is a GLP-1 agonist. 00:30 GLP-1, glucagon like peptide 1, functions under the category of gastrointestinal incretin hormones that helps you process the foods you eat. It improves insulin sensitivity. Decreases glucagon. 01:30 About 80% of the mechanisms of bariatric surgery is by amplifying the release of incretin hormones. 02:00 There was a 14% loss of body weight in study participants. 02:50 Semiglutide exerts stress on pancreatic beta cells, with an increased prevalence of pancreatitis and potentially pancreatic cancer. 04:40 GIP and GLP-1 are released after eating to increase insulin secretion from beta cells and prevent post-meal glucose excursions. 05:50 The diminished activity of GIP and GLP-1 is a feature of type-2 diabetes, beta cell insulin resistance, an obesity. 07:10 Exercise increases the release of gastrointestinal incretin hormones. 07:25 Berberine increases gut hormones and changes your microbiome. 07:40 These incretin hormones control the ecosystem of your gut microbiome and can improve function of immune cells around your gut. 08:10 Bifidobacterium can lead to a healthier GI incretin response. 09:00 GABA and L-glycine. 09:45 Protein and fat. 10:30 Polyphenols    

Om Podcasten

High Intensity Health features breakthrough health tips and hacks from respected authorities in the Fitness, Nutrition and Functional Medicine fields. Our expert guests have shared insider information that has helped thousands of Moms, Dads, Executives, Health Care Professionals and High-Performing Athletes optimize their metabolism, belly fat, gut bacteria, immune system,both physical and mental performance and overall health. No matter where you sit on the health and nutrition spectrum, you’ll benefit from our cutting-edge discussions, 2-days per week.