Midday News Brief for Monday, October 21st

Top U.S. drug distributors have reached a $260 million settlement with two Ohio counties over blame for fueling the nation's opioid crisis. British Prime Minister Boris Johnson fails to secure a vote of support from Parliament on his Brexit deal. WikiLeaks founder Jullian Assange's request for a delay in his extradition hearing with the U.S. is denied. J.R. Whalen reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

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The top business headlines from The Wall Street Journal, three times daily. Whether it’s the latest on overseas markets, economic news out of Washington or closing numbers from Wall Street, you'll be in the know in a flash.