Blindness, Schizophrenia, and Autism

https://astralcodexten.substack.com/p/blindness-schizophrenia-and-autism   Some weird psychiatric trivia: no congenitally blind person ever gets schizophrenia (journal article, popular article). “Trivia” is exactly the right word for this fact; it’s undeniably interesting, but what do you do with it? So far nobody has done anything, other than remark “hmm, that’s funny”. I was thinking about this recently in the context of the diametrical model of autism vs. schizophrenia. This is itself pretty close to psychiatric trivia - a lot of features of schizophrenia and autism seem to be opposites of each other. As I put it here: Many of the genes that increase risk of autism decrease risk of schizophrenia, and vice versa. Autists have a smaller-than-normal corpus callosum; schizophrenics have a larger-than-normal one. Schizophrenics smoke so often that some researchers believe they have some kind of nicotine deficiency; autists have unusually low smoking rates. Schizophrenics are more susceptible to the rubber hand illusion and have weaker self-other boundaries in general; autists seem less susceptible and have stronger self-other boundaries. Autists can be pathologically rational but tend to be uncreative; schizophrenics can be pathologically creative but tend to be irrational. The list goes on.

Om Podcasten

The official audio version of Astral Codex Ten, with an archive of posts from Slate Star Codex. It's just me reading Scott Alexander's blog posts.