Treatment After CDK4/6 Inhibitors

CDK4/6 inhibitors are used to treat both early-stage and advanced-stage hormone receptor-positive, HER2-negative breast cancer.  The CDK4/6 inhibitors are: Ibrance (chemical name: palbociclib) Kisqali (chemical name: ribociclib) Verzenio (chemical name: abemaciclib) At the 2023 San Antonio Breast Cancer Symposium, Dr. Stephanie Graff moderated an educational session to help people and their doctors decide on treatments after a CDK4/6 inhibitor has stopped working. Listen to the podcast to hear Dr. Graff explain: how the oral SERD, Orserdu (chemical name: elacestrant), might be used how PARP inhibitors, such as Lynparza (chemical name: olaparib) or Talzenna (chemical name: talazoparib) might be used why using a CDK4/6 inhibitor after another CDK4/6 inhibitor probably won’t be used

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Breastcancer.org is a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer. Our mission is to help women and their loved ones make sense of the complex medical and personal information about breast cancer, so they can make the best decisions for their lives. Breastcancer.org podcasts offer unique insights on prevention, treatment, research, and other breast cancer topics from our medical experts and invited guests.