Genomics and Health Outcomes (with Noor Siddiqui)

Read the full transcript here. (https://podcast.clearerthinking.org/episode/056/#transcript) • Why has there been such an explosion of progress in genomics recently? What's the right way to think about how genes affect the likelihood of experiencing certain health outcomes? How can people mitigate genetic risks for their potential children? What sorts of moral obligations (if any) do parents have to mitigate potential genetic risks for their children? How does Orchid's focus differ from other companies in the same space? What is "junk" DNA? What percentage of our genes are identical to our siblings, to other humans, and even to other animals? • Noor Siddiqui is the Founder and CEO of Orchid (https://www.orchidhealth.com/), a reproductive technology company. Prior to Orchid, Noor was an AI researcher at Stanford where she worked on applications of deep learning to genomics with Anshul Kundaje and computer vision applied to medical imaging with Sebastian Thrun. Noor has spoken internationally about her work at the intersection of technology and medicine at events like Milken's Global Conference, WebSummit, and Kaiser Permanente's Executive Leadership Summit. Her work has been covered by The Washington Post, Forbes, TechCrunch, among other outlets. Noor is also a recipient of the Thiel Fellowship, a grant program spawned by Paypal founder and Facebook board member, Peter Thiel, supporting breakthrough technology companies. Noor earned her M.S. and B.S. in Computer Science from Stanford University. Follow her on Twitter (https://twitter.com/noor_siddiqui_), connect with her on LinkedIn (https://www.linkedin.com/in/noorsiddiqui/), visit her website (https://noorsiddiqui.com/), or email her at noorsiddiqui@orchidhealth.com (mailto:noorsiddiqui@orchidhealth.com). • Staff • Spencer Greenberg (https://www.spencergreenberg.com/) — Host / Director • Josh Castle (mailto:joshrcastle@gmail.com) — Producer • Ryan Kessler (https://tone.support/) — Audio Engineer • Uri Bram (https://uribram.com/) — Factotum • Janaisa Baril (mailto:janaisabaril@gmail.com) — Transcriptionist • Music • Broke for Free (https://freemusicarchive.org/music/Broke_For_Free/Something_EP/Broke_For_Free_-_Something_EP_-_05_Something_Elated) • Josh Woodward (https://www.joshwoodward.com/song/AlreadyThere) • Lee Rosevere (https://archive.org/details/MusicForPodcasts04/Lee+Rosevere+-+Music+for+Podcasts+4+-+11+Keeping+Stuff+Together.flac) • Quiet Music for Tiny Robots (https://www.freemusicarchive.org/music/Quiet_Music_for_Tiny_Robots/The_February_Album/05_Tiny_Robot_Armies) • wowamusic (https://gamesounds.xyz/?dir=wowamusic) • zapsplat.com (https://www.zapsplat.com/music/summer-haze-slow-chill-out-house-track-with-a-modern-pop-feel-warm-piano-chords-underpin-the-track-with-warm-pads-and-a-repetitive-synth-arpeggio/) • Affiliates • Clearer Thinking (https://www.clearerthinking.org/) • GuidedTrack (https://guidedtrack.com/) • Mind Ease (https://mindease.io/) • Positly (https://positly.com/) • UpLift (https://www.uplift.app/) [Read more: https://podcast.clearerthinking.org/episode/056/noor-siddiqui-genomics-and-health-outcomes]

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Clearer Thinking is a podcast about ideas that truly matter. If you enjoy learning about powerful, practical concepts and frameworks, wish you had more deep, intellectual conversations in your life, or are looking for non-BS self-improvement, then we think you'll love this podcast! Each week we invite a brilliant guest to bring four important ideas to discuss for an in-depth conversation. Topics include psychology, society, behavior change, philosophy, science, artificial intelligence, math, economics, self-help, mental health, and technology. We focus on ideas that can be applied right now to make your life better or to help you better understand yourself and the world, aiming to teach you the best mental tools to enhance your learning, self-improvement efforts, and decision-making. • We take on important, thorny questions like: • What's the best way to help a friend or loved one going through a difficult time? How can we make our worldviews more accurate? How can we hone the accuracy of our thinking? What are the advantages of using our "gut" to make decisions? And when should we expect careful, analytical reflection to be more effective? Why do societies sometimes collapse? And what can we do to reduce the chance that ours collapses? Why is the world today so much worse than it could be? And what can we do to make it better? What are the good and bad parts of tradition? And are there more meaningful and ethical ways of carrying out important rituals, such as honoring the dead? How can we move beyond zero-sum, adversarial negotiations and create more positive-sum interactions?