Volunteering to be infected with COVID — for science! (with Josh Morrison)

Read the full transcript here. (https://podcast.clearerthinking.org/episode/099/#transcript) • How can we develop vaccines more quickly? What kinds of study designs are used (or could be used) during vaccine development? In pandemic situations, we need to roll out vaccines quickly; but even if we can develop and test a vaccine quickly and thoroughly, how confident can we be that there won't be long-term risks? Between ethics and pragmatics, which facet should communicators emphasize when trying to convince organizations and institutions to adopt certain vaccine development strategies? Informed consent is, of course, a hugely important requirement for using human volunteers in challenge trials; so if some people are informed, eager, and willing to volunteer their health and safety for such trials in order to aid vaccine development, then why aren't they being used more (if at all)? Since IRBs are often "all brakes and no gas", could they be given powers to accelerate research in addition to their current powers to slow or halt research? How can bioethics reviews be improved? • Josh Morrison is a serial social entrepreneur and aspiring effective altruist who has founded 1Day Sooner, Waitlist Zero, and the Rikers Debate Project. His work — in the fields of clinical trials, living organ donation, and criminal justice reform — focuses on empowering particular identity groups (research participants, kidney donors, and incarcerated people) to improve decision-making processes so as to achieve impactful policy. His projects have been covered globally in outlets such as the New York Times, CNN, the Financial Times, the BBC, Der Spiegel, Asahi Shimbun, and the South China Morning Post. His writing has been published in the Washington Post, the American Journal of Bioethics, Clinical Infectious Disease, Vaccine, Risk Analysis, Vox, STAT News, and BMJ Opinion. You can email him at josh@1daysooner.org (mailto:josh@1daysooner.org). • Staff • Spencer Greenberg (https://www.spencergreenberg.com/) — Host / Director • Josh Castle (mailto:joshrcastle@gmail.com) — Producer • Ryan Kessler (https://tone.support/) — Audio Engineer • Uri Bram (https://uribram.com/) — Factotum • Janaisa Baril (mailto:janaisabaril@gmail.com) — Transcriptionist • Music • Broke for Free (https://freemusicarchive.org/music/Broke_For_Free/Something_EP/Broke_For_Free_-_Something_EP_-_05_Something_Elated) • Josh Woodward (https://www.joshwoodward.com/song/AlreadyThere) • Lee Rosevere (https://archive.org/details/MusicForPodcasts04/Lee+Rosevere+-+Music+for+Podcasts+4+-+11+Keeping+Stuff+Together.flac) • Quiet Music for Tiny Robots (https://www.freemusicarchive.org/music/Quiet_Music_for_Tiny_Robots/The_February_Album/05_Tiny_Robot_Armies) • wowamusic (https://gamesounds.xyz/?dir=wowamusic) • zapsplat.com (https://www.zapsplat.com/music/summer-haze-slow-chill-out-house-track-with-a-modern-pop-feel-warm-piano-chords-underpin-the-track-with-warm-pads-and-a-repetitive-synth-arpeggio/) • Affiliates • Clearer Thinking (https://www.clearerthinking.org/) • GuidedTrack (https://guidedtrack.com/) • Mind Ease (https://mindease.io/) • Positly (https://positly.com/) • UpLift (https://www.uplift.app/) [Read more: https://podcast.clearerthinking.org/episode/099/josh-morrison-volunteering-to-be-infected-with-covid-for-science]

Om Podcasten

Clearer Thinking is a podcast about ideas that truly matter. If you enjoy learning about powerful, practical concepts and frameworks, wish you had more deep, intellectual conversations in your life, or are looking for non-BS self-improvement, then we think you'll love this podcast! Each week we invite a brilliant guest to bring four important ideas to discuss for an in-depth conversation. Topics include psychology, society, behavior change, philosophy, science, artificial intelligence, math, economics, self-help, mental health, and technology. We focus on ideas that can be applied right now to make your life better or to help you better understand yourself and the world, aiming to teach you the best mental tools to enhance your learning, self-improvement efforts, and decision-making. • We take on important, thorny questions like: • What's the best way to help a friend or loved one going through a difficult time? How can we make our worldviews more accurate? How can we hone the accuracy of our thinking? What are the advantages of using our "gut" to make decisions? And when should we expect careful, analytical reflection to be more effective? Why do societies sometimes collapse? And what can we do to reduce the chance that ours collapses? Why is the world today so much worse than it could be? And what can we do to make it better? What are the good and bad parts of tradition? And are there more meaningful and ethical ways of carrying out important rituals, such as honoring the dead? How can we move beyond zero-sum, adversarial negotiations and create more positive-sum interactions?