Finerenone's Role in Heart Failure from ESC Congress Data
Live from ESC Congress 2024! In this edition of Don’t Miss a Beat, Stephen Greene, MD, an advanced heart failure specialist at Duke University School of Medicine, discusses the prospect of finerenone in treatment algorithms for heart failure with Muthiah Vaduganathan, MD, MPH, codirector of the Center for Cardiometabolic Implementation Science of Brigham and Women’s Hospital, based on data from the meeting, including FINEARTS-HF, FINE-HEART, and an analysis on MRA use in heart failure. Chapters 00:00 - Welcome and Introduction 01:18 - FINEARTS-HF Study Design and Patient Population 03:04 - Inclusion of Hospitalized Patients 04:43 - Primary and Secondary Endpoints 05:56 - Challenges in Achieving Statistical Significance 07:39 - Health Status Improvement and Additional Analyses 10:01 - Combination Therapy and Future Trials 12:20 - Hyperkalemia and Steroidal vs. Non-Steroidal MRAs 15:30 - Conclusion and Acknowledgments