Consensus on B-lactamases (AAC ed.)

This episode is dedicated to the memory of the late George A. Jacoby, who was a pillar in the B-lactamase research community and a leader in the field of antimicrobial resistance. Assigning names to b-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new b-lactamase genes. In November 2021 an international group of b-lactamase experts met virtually to develop a consensus for the way naturally-occurring b-lactamase genes should be named. Topics discussed: The inconsistencies in B-lactamase nomenclature Guidelines for publication of new alleles and newly discovered B-lactamases  Future needs of consensus among the b-lactamase community Guests: Patricia Bradford PhD., Antimicrobial Development Specialists LLC Karen Bush PhD, Professor of Practice, Biotechnology and Interim Director, Biotechnology Program, Indiana University. Robert Bonomo MD, Professor Case Western Reserve University, Director VA CARES Research Collaborative Links: Consensus on β-Lactamase Nomenclature https://journals.asm.org/doi/10.1128/aac.00333-22 Visit journals.asm.org/journal/aac to browse issues and/or submit a manuscript.

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Editors in Conversation is the official podcast of the American Society for Microbiology Journals. Editors in Conversation features discussions between ASM Journals Editors, researchers and clinicians working on the most cutting edge issues in the microbial sciences. Topics include laboratory diagnosis and clinical treatment of infectious diseases, antimicrobial resistance, epidemiology of infections, multidrug-resistant organisms, pharmacology of antimicrobial agents, susceptibility testing, and more. The podcast is directed to microbiologists, infectious diseases clinicians, pharmacists and basic, clinical and translational researchers interested in the microbial sciences. A particular emphasis is on basic, epidemiological and pharmacological aspects of infectious diseases, including antimicrobial resistance and therapeutics.