Guiterrez C.: eosinophilic oesophagitis (EOE)

Today in the ESPGHAN podcast series we hear from Dr Carolina Gutiérrez Junquera of the Universidad Autónoma de Madrid on eosinophilic oesophagitis (EOE).  Dr Gutiérrez Junquera passed in her training through the Complutense University of Madrid and its affiliated hospitals.  After a fellowship in the San Francisco bay area, she went home to Spain to develop her interest in various aspects of EOE.  She has become prominent as an organiser and evaluator of multi-institutional studies of this disorder.  At present she is investigating proton-pump inhibitor (PPI) use in EOE, with focus on several questions:  What is the rôle of PPIs in treatment of children with EOE ?  What factors, pharmacogenetic and clinical, may predict PPI response in children with EOE ?  What do literature reviews and accumulated experience to date suggest be researched in EOE ?  Finally, what are the most important changes in the updated ESPGHAN guidelines on diagnosis and management of EOE ?  Today’s discussion tries to touch on these various elements – although not necessarily in that order.  Literature : Gutiérrez-Junquera C et al.  Proton pump inhibitor therapy in pediatric eosinophilic esophagitis:  Predictive factors and long-term step-down efficacy.  J Pediatr Gastroenterol Nutr 2023 Feb 1; 76(2):191-198.  doi: 10.1097/MPG.0000000000003660.  Epub 2022 Nov 23.  PMID:  36416845.   Franciosi JP et al.  Medical treatment of eosinophilic esophagitis.  Cochrane Database Syst Rev 2023 Jul 20; 7(7):CD004065.  doi:  10.1002/14651858.CD004065.pub4.  PMID:  37470293.  PMCID:  PMC10358040. Papadopoulou A et al.  Joint ESPGHAN / NASPGHAN guidelines on childhood eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis.  J Pediatr Gastroenterol Nutr 2024 Jan 78(1):122-152.  doi: 10.1097/MPG.0000000000003877.  Epub 2023 Jul 4.  PMID:  38291684. Dr. Guiterrez favourite song: Hoy puede ser un gran día - Joan Manuel Serrat https://open.spotify.com/track/5YxgSArh0FDP0CEDuZcYnC?si=d70a2941550b48c9  ESPGHAN favourite Songs can be found on Spotify https://open.spotify.com/playlist/0YIHKjxITLEm9XNyHyypTo 

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Stay updated with the latest developments in Paediatric Gastroenterology, Hepatology, and Nutrition (PGHN) and get to know the experts behind the research and our organisation. The official podcast of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) explores cutting-edge studies, practice management strategies, and more. Join us three times a month for insightful interviews and commentary with leading professionals in the field, designed to enhance your knowledge and advance your expertise. Our podcast features specialists from around the world, with a particular emphasis on the European community. This podcast is hosted by the ESPGHAN Education Committee. Disclaimer: Opinions expressed in this podcast are those of the guest invited and do not necessarily reflect the views or positions of ESPGHAN. These opinions are based on information and scientific data available at the time of recording and may change as research in the field advances. New Episodes 1st, 10th  and 20th of the Month. For feedback, contact us: office@espghan.org | Playlist: ESPGHAN favourite Songs can be found on Spotify https://open.spotify.com/playlist/0YIHKjxITLEm9XNyHyypTo