Ep. 367 The Metabolic Health Crisis & GLP-1s with Dr. Anurag Singh

I am delighted to reconnect with Dr. Anurag Singh today, the Chief Medical Officer at Timeline Nutrition. He joined me once before on Episode 268.  I invited Dr. Singh back to discuss the latest research on GLP-1 agonists like Wegovy, Semaglutide, and Ozempic, which are gaining significant traction with projected sales exceeding $100 billion by 2030, potentially affecting 9% of the US population. In our conversation, we explore the contributors to our metabolic health crisis by looking at the research surrounding GLP-1 agonists, the physiology of GLP-1 peptides, and the influencing elements Dr. Singh refers to as the trifecta. We dive into the loss of muscle mass and strength, sarcopenia, and frailty associated with these drugs, and Dr. Singh shares his concerns about their impact on bone health, the gut microbiome, and their use in younger patients. We also get into lifestyle measures, mitochondrial health, hallmarks of aging, Akkermansia, and the importance of advocacy and patient empowerment.  Today’s compelling and invaluable discussion with Dr. Anurag Singh highlights crucial insights into GLP-1 agonists and their broader health implications. I know it will provide significant value for our listeners. IN THIS EPISODE YOU WILL LEARN: Dr. Singh breaks down what GLP-1 agonist drugs are and how they work. How our modern-day lifestyles contribute to poor metabolic health The benefits and side-effects of using GLP-1 agonist treatments for improving metabolic health Why strength training is essential for preventing muscle loss and frailty in middle-aged women What are the potential long-term effects of SARMs on muscle mass and health? Why dietary counseling is essential for those taking GLP-1 agonist drugs The benefits of supplements for boosting mitochondrial health  Dr. Singh discusses a research study on combining lithium with GLP-1 agonists to improve the muscle quality of those with muscle-wasting conditions. Why akkermansia is essential for GLP production   Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia’s website  Submit your questions to support@cynthiathurlow.com Connect with Dr. Anurag Singh Timeline Mitopure Email Dr. Singh: asingh@amazentis.com  Previous Episode Mentioned Ep. 268: Understanding the Biology of Aging with Evolved Supplementation and Nutrition, featuring Dr. Anurag Singh

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Welcome to the Everyday Wellness podcast with Cynthia Thurlow! Cynthia Thurlow is a nurse practitioner, author of the best selling book Intermittent Fasting Transformation: IF45, 2x TEDx speaker, with her second talk having more than 10 million views, and the host of Everyday Wellness Podcast. With over 20 years experience in health and wellness, Cynthia is a globally recognized expert in intermittent fasting and women’s health, and has been featured on ABC, FOX5, KTLA, CW, Medium, Entrepreneur, and The Megyn Kelly Show. Her mission is to educate women on the benefits of intermittent fasting and overall holistic health and wellness, so they feel empowered to live their most optimal lives. Her goal with Everyday Wellness is to help her listeners make simple changes to their everyday lives that will result in improved overall wellness and long term health.