36. AMA#2: Acid/base balance, APOE4/FTO, omega-3s, carnivore diet types, the problem with broccoli and more!

It’s my book’s birthday week! The Carnivore Code has arrived!    This week’s podcast is an intense AMA I did for Ben Greenfield’s show which I reposting here. As you can see from the time stamps, in this monologue I cover a LOT of ground and dig into many of the common questions which arise on a carnivore diet.    Time Stamps:  8:10 Start of the podcast 9:30 How would Paul define a carnivore diet? 11:25 Spectrum of plant toxicity. 15:40 Nose to tail carnivore. 17:00 Getting enough protein on a carnivore diet. 21:10 How does a carnivore diet affect athletic performance? 21:55 Faster study. 28:25 Effect of 4 week very low carbohydrate diet on high intensity interval training responses  29:45 Keto adaptation enhances exercise performance. Body composition responses to training of endurance athletes (study). 32:20 Salt requirements on low carbohydrate diets.   34:20 Sources of iodine on a carnivore diet. 35:40 Dangers of excess iodine. 36:30 Sustainability of a carnivore diet.  40:00 Regenerative agriculture. 46:10 Hormesis and xenohormesis. 52:40 Uric acid and glutathione levels during short term cold exposure (study). 54:10 Sulforaphane. 56:40 Activation of  NRF2 pathways with environmental hormesis. 1:00:40 Sirtuin pathway activation and ketosis. 1:04:00 Fruit and vegetable depletion studies. 1:10:35 Negative effects of resveratrol and curcumin.(studies). 1:15:20 Can one's PH level get too acidic on a carnivore diet due to the high protein consumption ? 1:19:10 Potential renal acid load of foods and its influence on ph (study)  1:19:50 Effect of low carbohydrate high protein diet on acid base balance, stone forming propensity, and calcium metabolism (study). 1:23:00 Essential and toxic metals in animal bone broth (study). 1:25:00 Effects of a supplement rich in alkaline minerals on acid base balance in humans (study) 1:26:20 Do ketones increase acidity in the blood? 1:27:10 Statement on high protein diets and bone health. 1:28:20 IGF1 and MTOR. 1:32:35 Carnivore diet and APOE4 gene. 1:36:00 Studies on Simonae people. 1:40:30 Case study: APOE4  1:42:40 Study on APOE4 and susceptibility to insulin resistance. 1:43:45 FTO polymorphism and a carnivore diet. 1:48:40 What Paul eats in a day.

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Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. I hope you’ll join me on this journey.