Loud Thoughts: Depression, Anxiety, ADHD and the Default Mode Network [Archive]

We revisit a classic episode to understand the circuitry of the self as we uncover the neurological pathways behind the Ego and explain what the Default Mode Network is. Topics covered: What the hell is the Default Mode Network The Brain Pathways of Anxiety and Depression The imbalances causing ADHD How modern medicines interact with the brain The effect of meditation and psilocybin on the DMN Starting with Hans Berger's pioneering work with EEG this episode covers the history of Default Mode Network discovery, its role in ADHD symptoms, and the impact of Default Mode Network on depression. We also explore the connection between DMN and anxiety disorders and discuss the benefits of therapeutic interventions targeting the Default Mode Network. Learn how modern neuroscience uses DMN insights to enhance psychiatric treatments and the overall understanding of mental health. ---- Advertisers BetterHelp The world's largest online therapy provider ⁠⁠⁠BetterHelp.com/GrowthMindset⁠⁠⁠ - 10% off 1st month Liquid I.V. Sugar-free hydration for any occasion ⁠⁠⁠Liquid-IV.com⁠⁠⁠ - 20% off with code GROWTH ---- NEW SHOW - How to Change the World Sam's new show can be found on major podcast players: Spotify - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/1Fj3eFjEoAEKF5lWQxPJyT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Apple - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/how-to-change-the-world-the-history-of-innovation/id1815282649⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ YouTube - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@HowToChangeTheWorldPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Can't find it on your player? RSS feed - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://feeds.acast.com/public/shows/682b3b86696b5d1232d698a8⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ---- UPGRADE to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Premium⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠: 🏖️ Ad-free listening 🤘 Support the show 🔓 Exclusive AMAs and bonus content 💬 Community Discord ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GrowthMindset.Supercast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in Touch 👋 Free Call - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Schedule Link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - https://cal.com/samwebster/mindset 📧 Email - GrowthMindsetPodcast (@) gmail,com Growth Mindset Psychology: Sam Webster explores the psychology of happiness, satisfaction, purpose, and growth through the lens of self-improvement. 📺 Watch - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube (Growth Mindset)⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🛜 Website - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Growth Mindset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Further Reading ⁠Default Mode Network on Wikipedia⁠ ⁠Where is the Default mode network⁠ Paper: ⁠The Brains Default Mode Network⁠ Paper: ⁠Schizophrenia and DMN ⁠ Paper: ⁠Autism and DMN⁠ ⁠Theory of Mind⁠ Related Episodes How to Stop Catastrophizing Science of Psilocybin Therapy w/ Gabriel Charalambides Psilocybin Therapy ⁠John Hopkins Research⁠ Legal treatment in the USA - ⁠Odyssey⁠ Meditation Retreats Paper: ⁠Meditation effect on the DMN⁠ Book: ⁠Why Buddism is True⁠ (Evolutionary Psychology of Meditation) 10 day Vipassana (free) - ⁠Dhamma.org⁠⁠ Chapters: 00:00 Introduction to the Default Mode Network 02:04 Hans Berger and history of EEG and brain mapping 04:49 Discovery of the Default mode network 06:14 What is the default mode network? 06:33 #1 Self-referential thought 07:00 #2 Theory of mind 07:43 #3 Autobiographical memory 08:12 #4 Envisioning future scenarios 08:32 #5 Mind wandering and daydreaming 09:16 #6 Creativity 10:21 Depression and the brain 11:28 Anti Depressant medication and the DMN 12:41 Anxiety 14:08 Anti Anxiety medication and Benzodiazepines 15:27 ADHD 16:16 ADHD medication and stimulants 18:03 How Meditation Regulates the DMN 20:34 Psilocybin impact on the DMN 22:41 Wrap up Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Most self-help advice is guesswork dressed up as wisdom. We dig into psychology, neuroscience, and behavioral science to find what actually changes lives. WHY LISTEN? Over 8 million downloads because we answer the questions that matter: How do I build mental strength? What creates lasting motivation? How can I understand my own mind well enough to work with it, not against it? This podcast is for curious skeptics who want frameworks backed by psychology studies, not Instagram quotes. Whether you're navigating procrastination, building self-discipline, or designing your own philosophy for a life well lived—we explore the hidden psychology behind real change. WHAT YOU'LL GET Mental models and simple techniques from cognitive psychology, positive psychology, and ancient wisdom traditions like Stoicism and Buddhism. Being a human can be confusing, learning about it doesn’t have to be. We cover everything from emotional intelligence and habit formation to brain health and the nervous system. WHAT YOU DON’T GET No pseudoscience. No oversimplified "hacks." No hustle porn. Just practical insights on mindset improvement, self-development, and human psychology that respect your intelligence and mental health. THE APPROACH Instead of telling you what to think, we explore how thinking works. Armed with psychology studies, social science research, and relentless curiosity, we uncover the mechanics of belief change, attitude change, and personal development. Success is personal. You might want to leverage your neurodiverse strengths, build a business, or simply discover how to be happier. We provide the mental frameworks to pursue your definition of success with mental strength and self-care that fits your life. YOUR HOST I'm Sam Webster Harris—a lifelong learner with ADHD and an obsession with finding answers to hard questions. After launching businesses, traveling the world, and nearly dying a few times, I concluded that psychology and science are where real wisdom lives. This show is my excuse to dive deep into health and fitness research, behavioral psychology, and cool science while helping you build genuine self-discipline and motivation. PREMIUM Go ad-free and access exclusive content, AMAs, and our community Discord. Growth Mindset Premium PAST SERIES Previous guests include Olympians, Scientists, Billionaires, and Sam's Mum. Past series: — Psychology vs Stoicism — Time Management for Busy Mortals — Independence and Knowing Yourself — Cognitive Biases and Rational Thinking — Psychology of Connection and Relationships — Carol Dweck and the Multiverse of Mindsets — Addiction and Behaviour Change — Nervous System Mastery and Polyvagal Theory — Mental Strength and Self-Discipline