Longevity Drugs You Should Consider for Immune Health

Metformin and Rapamycin, two popular longevity drugs, have been shown to support immune health in elderly and high-risk subjects as well as decrease mortality in persons infected with COVID-19. We discuss the science and rationale for prophylactic blood sugar health support in non-diabetics for longevity and immune health.  Support your fasting lifestyle with Berberine HCl & Alpha Lipoic Acid by by MYOXCIENCE Nutrition: https://bit.ly/berberine-biotin-ala-stack Use code Podcast to save Related Podcast: Latest Breakthroughs In the Biology of Aging with Matt Kaeberlein, PhD   Time Stamps: 0:00 intro 0:38 mTOR inhibitors 1:15 Low Side effect profile 2:19 Metformin and influenza 2:50 Metabolic and immune health are one in the same 3:15 Aging and Immune Competence 3:52 Microdosing mTOR inhibitors 4:31 Dog Aging Project 5:07 Aging and Immunity 6:10 T Cells are Essential 6:55 Metformin was initially helpful for Influenza 8:11 Why chronic inflammation is bad 9:39 Pulsing mTOR inhibitors 13:38 Electrolytes and Creatine 14:19 Drugs are not always bad 15:28 Poor blood sugar control is a problem 18:20 Metformin and B Vitamins 19:15 Metformin and C*19   Articles Mentioned: Bischof, E., C Siow, R., Zhavoronkov, A., & Kaeberlein, M. (2021). The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19. The Lancet Healthy Longevity, 2(2), e105–e111. http://doi.org/10.1016/S2666-7568(20)30068-4   Bramante, C. T., Buse, J., Tamaritz, L., Palacio, A., Cohen, K., Vojta, D., et al. (2021). Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity. Journal of Medical Virology, 93(7), 4273–4279. Kruglikov, I. L., Shah, M., Elife, P. S.,. (2020). Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions. Elifesciences.org. metabolism, A. S. D.,. (2020). Metformin and COVID-19: from cellular mechanisms to reduced mortality. Nutrition, Metabolism and Cardiovascular Diseases. http://doi.org/10.1016/j.diabet.2020.07.006  

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High Intensity Health features breakthrough health tips and hacks from respected authorities in the Fitness, Nutrition and Functional Medicine fields. Our expert guests have shared insider information that has helped thousands of Moms, Dads, Executives, Health Care Professionals and High-Performing Athletes optimize their metabolism, belly fat, gut bacteria, immune system,both physical and mental performance and overall health. No matter where you sit on the health and nutrition spectrum, you’ll benefit from our cutting-edge discussions, 2-days per week.