Cannabis and Coping: A Mixed Relationship

In this episode Preston and Margaret explore the endocannabinoid system, cannabis, and its impact on mental health. They break down the science behind CB1 and CB2 receptors, explain why marijuana affects people so differently, and discuss the complex relationship between THC, CBD, and dopamine. Along the way, they tackle myths about cannabis use, addiction, and medical marijuana, shedding light on what we actually know—and what remains a mystery due to historical barriers to research. Takeaways: The Endocannabinoid System is Vast and Mysterious: CB1 and CB2 receptors exist throughout the body, influencing pain, pleasure, nausea, and more—but the full scope of their role remains unclear. Marijuana’s Effects Depend on the User: Some people experience relaxation and appetite stimulation, while others develop anxiety, paranoia, or even worsening nausea with chronic use. The THC-to-CBD Ratio Matters: Over time, cannabis strains have been bred to increase THC potency, which may contribute to heightened psychiatric risks, including psychosis. Cannabis Can Have Severe Side Effects: Long-term use can lead to cannabinoid hyperemesis syndrome (CHS)—a condition causing severe nausea and vomiting—and may increase the risk of cannabis-induced psychosis in predisposed individuals. Medical Cannabis Outpaced the Research: While cannabis is now widely used for medical purposes, much of its effectiveness is anecdotal, and research on its long-term mental health impacts is still catching up. — Watch on YouTube: @itspresro Listen Anywhere You Podcast: Apple, Spotify, PodChaser, etc. — Produced by Dr Glaucomflecken & Human Content Get in Touch: howtobepatientpod.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Om Podcasten

You may have noticed a new trend lately. Everyone is loud and proud about their mental health struggles (and thank goodness)! For practitioners, this movement is as exciting as it is frustrating. As each mental health taboo falls by the wayside as it enters the cultural zeitgeist, a new aspect of our specialty thus emerges. One we just don’t have enough hours in the day to keep track of, let alone engage with. From better understanding our patients’ (and our own) relationships with their conditions in a changing world, it’s more important than ever that we learn: HOW TO BE PATIENT! Each week, join Dr. Preston Roche (Psychiatry Resident & Digital Influencer) and Dr. Margaret Duncan (Psychiatrist & Content Creator) on their quest to better understand the patients we dedicate our lives to and the evolving paths they’re bound to travel beyond the clinic. By engaging with stories and perspectives that challenge our shared understanding of a condition, we hope you’ll similarly gain new perspectives as we look at our patients, and their mental health struggles, with further nuance and empathy. (And with Dr. & Lady Glaucomflecken producing, we've been mandated to include plenty of weird medical jokes too). Speaking of which, a key part of this is hearing YOUR stories! What’s changed your understanding of patient care? Do you have an experience that shines new light on something we’ve discussed on-air? Get in touch at: howtobepatientpod.com