SCCM Pod-526 CCM: Alteplase Dosing in Pulmonary Embolism

Host Samantha Gambles Farr, MSN, AG-ACNP, FNP-C, RNFA, is joined by Roman Melamed, MD, to discuss the comparative effectiveness of reduced-dose versus full-dose alteplase for acute pulmonary embolism, focusing on patient outcomes and complications. They will highlight study findings on significant improvements in hemodynamic and respiratory parameters in both groups, with a lower rate of hemorrhagic complications in the reduced-dose group (Melamed R, et al. Crit Care Med. 2024;52:729-742). Dr. Melamed is a critical care intensivist and director of the Pulmonary Embolism Program at Abbott Northwestern Hospital in Minneapolis, Minnesota, USA, and an adjunct associate professor at the University of Minnesota.

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The Society of Critical Care Medicine (SCCM) Podcast features in-depth interviews with leaders in critical care. Experts discuss hot topics in intensive care with perspectives from all members of the critical care team. Guests include authors from SCCM’s peer-reviewed journals, Critical Care Medicine, Pediatric Critical Care Medicine, and Critical Care Explorations, as well as thought leaders within the field. This is a new and updated channel, formerly known as the iCritical Care Podcast All Audio Channel.