Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of brain tumors

Survival for glioblastoma remains very poor despite decades of research, with a 5-year survival of only 5%. Technological improvements that have revolutionized treatment of ischemic stroke and brain aneurysms have great potential in providing more precise and selective delivery of cancer therapeutic agents to brain tumors. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Stephen Chen (1)and Dr. Peter Kan (2) about their paper "Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of malignant brain tumors". The paper describes a technique using perfusion guidance to enhance the precision of endovascular super-selective intra-arterial (ESIA) infusions of mesenchymal stem cells loaded with Delta-24 in the treatment of glioblastoma. This technique enhances targeted super-selective delivery of therapeutic agents for brain tumors. Paper available online (https://jnis.bmj.com/content/14/6/533) and in June print issue of JNIS. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced by Leticia Amorim and edited by Brian O'Toole. (1) Interventional Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2) Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

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The Journal of NeuroInterventional Surgery (JNIS) Podcast is your source for a comprehensive look at the latest scientific research and literature in the field of neurointerventional surgery. Hosted by Editor-in-Chief, Dr. Felipe C. Albuquerque, each episode features in-depth interviews with authors and leading experts. Stay informed on the latest neurointerventional techniques for the treatment of a range of neurological and vascular problems including stroke, aneurysms, brain tumours, and spinal disorders. Subscribe here or listen on your favourite podcast platform. JNIS - jnis.bmj.com - is published by BMJ on behalf of the Society of NeuroInterventional Surgery. * The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.