Jason Karlawish: What next for Alzheimer's disease?

There has been "spectacular" progress in recent years in the understanding and treatment of Alzheimer's.  The progressive disease, which is the most common cause of dementia, a late-in-life decline in memory and cognitive ability, afflicts 50 million people around the world. Taking family members and other carers into account, that number increases exponentially.  The condition, for which there is currently no cure,  amounts to a modern day crisis, for all involved. In this episode of the LLAMA podcast, Dr Jason Karlawish, a gerontologist and professor of medicine and medical ethics and senior fellow of the Center for Bioethics at the University of Pennsylvania, says significant gains are being made with therapeutic treatments, but many hurdles remain.  The author of The Problem of Alzheimer's: How Science, Culture and Politics turned a Rare Disease into a Crisis, also argues that Alzheimer's is disease of our identity and a condition that raises fundamental, moral questions about what it means to lead a good life. Recorded: March 30, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:The difference between dementia and Alzheimer's disease.How can dementia be distinguished from the 'normal course of aging?"The work of the Penn Memory Center, with patients and their loved ones. Explaining medicine in the 'real world,' through the stories and experiences of people.Why patients and caregivers are the best teachers. Distinguishing between disease and disability. How stigma haunts the lives of people with dementia. Defining Alzheimers as once a rare disease, now a crisis. The "spectacular progress in science," dealing with Alzheimer's. "Living' with Alzheimer's rather than relying on drugs. Why is the risk of demential declining? The crisis of good quality care for Alzheimer's patients in the U.S.Regular exercise and a heart healthy diet to maiFit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifyTime-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams.  Use the code LLAMA at checkout- FlexBeam red light therapyRecharge Health is offering LLAMA listeners a discount on the purchase of FlexBeam, the wearable red light therapy device which targets key parts of the body to improve sleep, treat injuries and sooth aches and pains associated with aging. Discounts vary - see details of the current offer hereSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

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The Live Long and Master Aging (LLAMA) podcast is a weekly series of extended, one-to-one interviews, about human longevity. Hosted by Peter Bowes, leading scientists share their latest research into living a long and healthy life. We delve into the clinical trials and challenge new ideas. We also feature some remarkable people who have already mastered the art of aging. Hear about their insights into growing old, without feeling old, and the secrets of their longevity.