Christina Applegate and Jamie-Lynn Sigler On The Pain And Triumph of Living with MS

Actresses Christina Applegate and Jamie-Lynn Sigler have spent decades in the spotlight, with iconic roles on "Married With Children" and "The Sopranos". They've taken on a different role in recent years as the public faces of multiple sclerosis. Sigler was diagnosed when she was just 20 years old, but didn't publicly share her diagnosis until 2016. Applegate received her diagnosis less than four years ago. The two opened up to Hoda about the pain and triumph that has bonded them.

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Where do you draw your strength? Join TODAY’s Hoda Kotb as she continues on a journey of self-discovery and exploration of the resilience of the human spirit. Hoda hears from some of the people she admires most, and whose testimonies of compassion provide lessons for how to make space for whatever it is you may be seeking in life right now. Like Hoda, you’ll leave these talks stronger than when you started and inspired to make space for growth and change in your own life.