Chelsea Handler on How to Make Drastic Changes, Accept Your Mistakes, and What Turning 50 Means to Her!

Chelsea Handler (comedian, television host, bestselling author) opens up about her transformative journey, from her powerful lessons on sisterhood learned from a tense meeting with Jane Fonda to the moment she realized her tough exterior was holding her back. Mayim breaks down her latest book, “I’ll Have What She’s Having” and Chelsea’s dating history, including her break-up with Jo Koy. Chelsea reveals how confronting deep-rooted anger fueled by childhood grief led her to therapy and spirituality, giving her the strength to evolve and embrace new forms of healing. Plus, she shares how turning 50 has reshaped her perspective on life, relationships, and finding freedom in saying "no"—a life-changing shift that’s led her to enjoy the freedom of not having kids while still embracing the joys of being a "stepmom" to many.

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Mayim Bialik’s Breakdown is a quirky, informative, and interactive podcast breaking down the myths and misunderstandings about mental health and emotional well-being. Neuroscientist Mayim Bialik combines her academic background with vast personal experience to provide listeners with valuable practical advice focusing on removing the stigma surrounding mental health and encouraging an understanding of the mind-body connection. Nothing is off limits as Mayim breaks it down with an amazing collection of guests.