#14: Semaglutide and cardiovascular disease in non-diabetic patients, comparing intravascular imaging, functional, and angiographically guided coronary intervention, anticoagulation in patients with

In this episode of Medmastery’s Cardiology Digest, we delve into a trio of intriguing cardiology studies that raise as many questions as they answer. Whether you're a seasoned clinician or a medical student, these studies have implications that could influence your approach to patient care. STUDY #1: First, we turn our attention to the role of GLP-1 agonists in cardiovascular disease prevention among non-diabetic patients who are overweight or obese. With a focus on injectable semaglutide this study examines its cost-effectiveness and potential side effects. The findings might alter how we manage cardiovascular risk in these patients!  Lincoff AM et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med 2023 Nov 11; [e-pub]. (https://doi.org/10.1056/NEJMoa2307563) STUDY #2: Next, we’ll explore a compelling meta-analysis that could sway future guidelines and recommendations. They evaluated the outcomes of physiologic guidance and intravascular imaging in percutaneous coronary interventions (PCI), to see if these techniques improve patient outcomes beyond what’s possible with angiographic guidance alone. Kuno T et al. Comparison of intravascular imaging, functional, or angiographically guided coronary intervention. J Am Coll Cardiol 2023 Dec 5; 82:2167. (https://doi.org/10.1016/j.jacc.2023.09.823) STUDY #3: Finally, we’re going to examine the nuances of anticoagulation in patients with subclinical atrial fibrillation. The balance between preventing strokes and avoiding bleeding complications is a delicate one. With new data suggesting nuanced approaches, this segment will provide valuable insights for us when we’re prescribing or considering anticoagulation therapies. Healey JS et al. Apixaban for stroke prevention in subclinical atrial fibrillation. N Engl J Med 2023 Nov 12; [e-pub]. (https://doi.org/10.1056/NEJMoa2310234) Svennberg E. What lies beneath the surface — Treatment of subclinical atrial fibrillation. N Engl J Med 2023 Nov 12; [e-pub]. (https://doi.org/10.1056/NEJMe2311558) Join us to explore the potential impacts of these studies, the ongoing debates they spark within the cardiology community, and to see how these findings could influence your clinical decisions. Learn more with these courses: Percutaneous Coronary Intervention Essentials (6 CME) Percutaneous Coronary Intervention Essentials Workshop (6 CME) Show notes: Visit us at  https://www.medmastery.com/podcasts/cardiology-podcast.

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In 15 minutes or less, keep up to date on the latest studies and advancements in cardiology with the award-winning, leading clinical skills training platform, Medmastery! We’re recommended by the British Medical Association, and hundreds of thousands of clinicians around the world trust us to simplify complex information. We make it bite-sized, and easy to fit into your daily routine! In the complex and rapidly evolving field of cardiology, with new treatments and technologies emerging all the time, it can be tough to keep up with all the papers published on a daily basis. That's where our Cardiology Digest comes in. Our cardiology experts select the most important papers. Then we break them down into easy-to-understand, digestible nuggets that help you stay informed and empowered to make the right decisions for your patients. From heart disease to arrhythmias, we cover a range of topics—including cutting-edge diagnostic tools and treatment options—that are relevant to the field. So, if you're looking for a simple, accessible way to stay up to date with the latest trends and advancements in cardiology and medicine, tune in to Medmastery's Cardiology Digest! Visit us at www.medmastery.com!