How do skin creams penetrate the skin?

Garth wants to know, given the skin can block water from passing through it, how do certain skin creams allege to permeate into our body? James Tytko took on the question with help from Richard Guy, Professor of Pharmaceutical Sciences at the University of Bath... Like this podcast? Please help us by supporting the Naked Scientists

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Each week we set out to solve one of the world's weirdest, wackiest, funniest and funkiest scientific puzzles. And along with the answer there's a brand new question to think about for next time...