PREVIEW Aliquot #65: Concerns with chronic NSAID use

Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, such as aspirin, ibuprofen, naproxen, and others. Most NSAIDs, with the exception of aspirin, work by inhibiting the activity of a family of enzymes called cyclooxygenases, which drive inflammatory processes. But because these inflammatory processes can be beneficial in some contexts and because the drugs often elicit off-target effects, there are some concerns about their use.  In this Aliquot, I describe current recommendations and concerns surrounding NSAID use.  (00:00) Introduction (02:58) Daily aspirin use and cardiovascular disease risk (clip from Q&A #9) (07:02) The pros and cons of low-dose aspirin (clip from Q&A #30) (11:43) Aspirin use and metastatic cancer risk (13:46) Aspirin vs other NSAIDs (15:20) Effects of ibuprofen on the kidneys, stomach, and muscles (clip from Q&A #14) (18:52) NSAIDs, heart attack, and stroke (20:04) Alternatives to NSAIDs Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more. Learn more and sign up at: https://www.foundmyfitness.com/aliquot

Om Podcasten

This is the Aliquot Preview - a sneak peek into FoundMyFitness’s members-only podcast: The Aliquot. Learn more about The Aliquot at foundmyfitness.com/aliquot. Every month we release one free preview episode here so you can sample one of the many FoundMyFitness Premium Membership benefits. So what is an aliquot? An aliquot is a sample taken from a larger whole, that captures the essence of the entirety. FoundMyFitness Aliquots are short, members-only podcasts focused on single topics, curated and remixed to surface our richest content on the most popular topics like diet and nutrition, health span and life extension, exercise, fasting, ketosis, sauna and cold exposure, sleep and depression. Some episodes are edited excerpts, highlights, and informative moments taken from full interviews in the FoundMyFitness podcast (with a little more context from Dr Rhonda Patrick!) Other episodes are mash-ups and highlights from our regular Q&As with members. Become a FoundMyFitness Premium member to get access to weekly Aliquots, biweekly Science Digest emails, and monthly Q&As with Rhonda. Learn more at foundmyfitness.com/crowdsponsor.