How FLT3-ITDs & NPM1 Insertions Maneuver Into AML Using Lymphoid Enzyme TdT With Drs. Kim & Borrow

In this podcast, Contributing Editor Dr. Annette Kim has a conversation with Dr. Julian Borrow. They discuss Dr. Kim's Diffusion article from the March/April 2020 issue of The Hematologist. The article titled, "How FLT3-ITDs and NPM1 Insertions Maneuver Into AML Using the Lymphoid Enzyme TdT to Initiate Replication Slippage," discusses the prominent role of TdT in the generation of FLT3-ITD and NPM1c mutations in acute myeloid leukemia (AML). You can find her (and co-author, Dr. John LaMacchia's) Diffusion article online at www.hematology.org/Thehematologist/Diffusion/10277.aspx. Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

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The Hematologist is the member newsletter of American Society of Hematology (ASH). It is designed for the broad constituency of ASH, all working toward the ultimate goal of conquering blood diseases. The Hematologist updates readers about important developments in the field of hematology and highlights what ASH is doing for its members.