Are Sepsis Protocols Ready for AI?

How can we diagnose what we haven’t yet defined? Nicole welcomes Dr. Shamim Nemati and Dr. Gabriel Wardi to explore how artificial intelligence (AI) is reshaping sepsis detection. They dig into why existing definitions fall short, how data-driven tools can outperform traditional alerts, and where AI could take us next, from smarter antimicrobial stewardship to real-time clinical support. A conversation for anyone rethinking how we recognize and respond to sepsis. Featured Guests: Gabriel Wardi, MD, MPH, FACEP ( @WardiGabriel on X): Emergency medicine and critical care physician at UC San Diego focused on improving sepsis pathways, triage systems, and early intervention in acute care. Shamim Nemati, PhD (@ShamimNemati on X): Biomedical informatics researcher and AI scientist specializing in predictive analytics, machine learning, and sepsis risk modeling in real-time clinical settings. Key Takeaways: Clarify how artificial intelligence, machine learning, and traditional decision tools differ and how each is evolving to improve sepsis detection and antimicrobial stewardship. Explore how cutting-edge AI/ML models are helping close gaps in infection prevention, early sepsis detection, diagnostics, and resistance forecasting. Learn how these tools are being applied to risk prediction, therapy selection, and alert refinement across hospital workflows. Walk away with real-world examples and design insights to help improve diagnostic precision and clinical decision support in your own system. — Get in Touch: info@sepsis.org Or Visit Us At: SepsisPodcast.org Connect with Nicole on Socials: @nicolekupchik Connect with Sepsis Alliance on Socials: @sepsisalliance To Learn More About Sepsis, Visit EndSuperbugs.org Produced by: Human Content and Sepsis Alliance

Om Podcasten

Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.  Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR. Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way. The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming. A Sepsis Alliance Podcast Nursing CE Contact Hours Available - Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance.