TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells

TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server First gene therapy for hemophilia A approved (FDA) Luxurna, gene therapy for vision loss (FDA) Anti-RSV monoclonal antibody approved (FDA) Trial of single-dose Nirsevimab (NEJM) Letters read on TWiV 1028 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Phoenix hits 110 degrees for the 19th day in a row, setting national record Brianne – James Webb Telescope One Year Anniversary Photo Kathy – Drone awards photos Alan – WHO Film Festival winners Vincent – Thinking, Fast and Slow by Daniel Kahneman Listener Picks David – The Mass Extinction Debates: A Science Communication Odyssey Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

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TWiV is a weekly netcast about viruses - the kind that make you sick. Professors Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler and science writer Alan Dove and guests deconstruct viruses, how they cause illness, and dissect the latest research.